{"product_id":"pnc-27","title":"PNC-27","description":"\u003cp\u003e\u003cspan\u003ePNC-27 is often referred to as the anticancer peptide as it contains an HDM-2-binding domain that corresponds to resides 12-26 of p53, as well as a transmembrane-penetrating domain that kills cancer cells by inducing membranolysis. Current research has found that the peptide can successfully induce tumor cell necrosis in both solid and non-solid tissues dependent on the expression of HDM-2 and selective transmembrane pore formation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eMain Research Findings\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1) PNC-27 has the potential to induce tumor cell necrosis of a non-solid, tissue human leukemia cell line dependent on the expression of HDM-2 throughout the plasma membrane of tumor cells.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e2) The peptide PNC-27 successfully binds to HDM-2 resulting in the induction of selective membrane-pore formation and cancer cell lysis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePNC-27 is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. \u003c\/span\u003e\u003c\/p\u003e","brand":"Sunshine \u0026 Poppies Compounds","offers":[{"title":"Default Title","offer_id":48458348232898,"sku":"52","price":115.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0747\/0687\/8658\/files\/IMG-0470.png?v=1784405761","url":"https:\/\/sunshineandpoppiescompounds.com\/products\/pnc-27","provider":"Sunshine \u0026 Poppies Compounds","version":"1.0","type":"link"}